2-O-Ethyl Ascorbic Acid
INCI: 2-O-ETHYL ASCORBIC ACID
Also known as: 2-o-ethyl Ascorbic Acid
A stable vitamin C derivative that supports skin brightness and texture refinement
At a glance
Best For Skin Types
All, Oily, Combination, Mature
Addresses
Effective Concentrations
0.5-2%
Usage Frequency
Daily
What Is 2-O-Ethyl Ascorbic Acid?
2-O-Ethyl Ascorbic Acid is a stabilised derivative of vitamin C (ascorbic acid) created by attaching an ethyl group to the vitamin C molecule. This chemical modification makes it significantly more stable than pure ascorbic acid, which degrades easily when exposed to light, air, and water. The ingredient is oil-soluble, allowing it to penetrate the outer layers of skin more readily than water-soluble vitamin C forms.
Once absorbed into the skin, 2-O-Ethyl Ascorbic Acid is converted into active ascorbic acid through enzymatic processes, where it can then exert vitamin C's recognised effects on skin health and appearance.
Benefits for Your Skin
How It Works
The stabilised structure of 2-O-Ethyl Ascorbic Acid allows the ingredient to remain effective in formulations where pure vitamin C would degrade. Upon penetrating the skin, enzymatic processes convert it to its active form, ascorbic acid, which then becomes bioavailable to skin cells.
Once activated, vitamin C functions as an antioxidant, neutralising free radicals and supporting the skin's natural repair mechanisms. It also plays a role in collagen biosynthesis by acting as a cofactor for enzymes involved in collagen cross-linking and stabilisation, which may contribute to improved skin firmness and texture over time.
Clinical Evidence & References
Vitamin C derivatives, including 2-O-Ethyl Ascorbic Acid, have been studied for their effects on skin brightness, antioxidant protection, and collagen support. Research generally supports the efficacy of stabilised vitamin C forms, particularly at concentrations of 0.5 per cent and above, for producing measurable improvements in skin tone and texture.
However, evidence specific to 2-O-Ethyl Ascorbic Acid as a distinct ingredient is more limited compared to other vitamin C derivatives. Most studies focus on broader vitamin C activity rather than this particular chemical form. Its stability advantage over pure ascorbic acid is well-established in cosmetic chemistry, but comparative clinical data on consumer outcomes remains modest. Longer-term or head-to-head studies would help clarify its place among other vitamin C options.
How to Use
2-O-Ethyl Ascorbic Acid is typically used once daily, usually in the morning, to take advantage of its antioxidant properties during the day. Apply to clean, dry skin before other treatments. Because it is oil-soluble, it pairs well with serums or lightweight moisturisers. Avoid mixing with alkaline ingredients or strong actives in the same step, as this may reduce efficacy. Allow 5-10 minutes for full absorption before applying sunscreen, which is essential when using vitamin C products.
Safety & Precautions
Regulatory information
Standardised cosmetic-ingredient identifiers used by regulators.
Show identifiers
- INCI Name
- 2-O-ETHYL ASCORBIC ACID
- EC Number
- -
- Function
- Skin Conditioning
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