7-Dehydrocholesterol

INCI: 7-DEHYDROCHOLESTEROL

A cholesterol precursor that supports skin's natural vitamin D synthesis pathway

Best For Skin Types

All

Addresses

Barrier repair

Usage Frequency

Daily

What Is 7-Dehydrocholesterol?

7-Dehydrocholesterol is a naturally occurring sterol found in skin. It serves as the substrate for vitamin D3 production when skin is exposed to ultraviolet B (UVB) radiation. In cosmetic formulations, it functions as an emulsion stabiliser, skin conditioner, and viscosity controller rather than as a vitamin D source.

The ingredient is relatively uncommon in skincare products, appearing in approximately 0.1% of formulations. Its inclusion is typically intended to support the skin's structural integrity and formulation stability rather than to meaningfully boost vitamin D synthesis through topical application alone.

How It Works

Within the skin, 7-dehydrocholesterol is the immediate precursor to vitamin D3 synthesis when UVB light penetrates the epidermis. However, the concentration required for meaningful systemic vitamin D production through topical application is not typically achieved in skincare products.

In formulations, 7-dehydrocholesterol works primarily as a structural and functional ingredient, supporting emulsion chemistry and skin texture without requiring metabolic conversion. Any contribution to vitamin D status would be negligible compared to dietary intake or natural sun exposure.

Clinical Evidence & References

Research demonstrates that 7-dehydrocholesterol is essential for endogenous vitamin D3 synthesis in response to UVB exposure, with the skin capable of producing substantial amounts (up to 25,000 IU daily under adequate sun exposure). However, evidence specifically evaluating topically applied 7-dehydrocholesterol in skincare products is limited.

The ingredient's inclusion in cosmetic formulations appears to be driven primarily by its functional properties as an emulsifier and skin conditioner rather than by clinical data demonstrating efficacy for vitamin D supplementation via the skin. More research would be needed to determine whether topical application at typical cosmetic concentrations offers meaningful benefits beyond formulation stability.

How to Use

7-Dehydrocholesterol is typically a background ingredient in formulations rather than a star component, so no special application technique is required. Use products containing it as directed by the formulation instructions. For meaningful vitamin D support, prioritise adequate sun exposure (with appropriate UV protection) and dietary sources or supplementation if recommended by a healthcare professional.

Safety & Precautions

7-Dehydrocholesterol is generally well-tolerated in topical skincare formulations. No significant adverse effects have been reported at cosmetic concentrations.

How widely it's used

0.1%
of skincare products contain this ingredient .
Most common in: Moisturisers Sunscreens Treatments

Regulatory information

Standardised cosmetic-ingredient identifiers used by regulators.

Show identifiers
INCI Name
7-DEHYDROCHOLESTEROL
EC Number
207-100-5
Function
Emulsion Stabilising, Skin Conditioning, Viscosity Controlling

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