Acetone

INCI: ACETONE

A volatile solvent used to denature or dissolve other ingredients in skincare formulations

Best For Skin Types

All

Usage Frequency

As directed on product label

What Is Acetone?

Acetone is a simple organic solvent—a colourless, volatile liquid that evaporates readily at room temperature. In skincare formulations, it functions primarily as a denaturant (a substance added to render an ingredient unsuitable for consumption) or as a solvent to help dissolve and incorporate other active compounds into a product.

You'll encounter acetone most commonly in nail products and some specialised skincare formulations where its rapid evaporation and dissolving properties are useful. Because it evaporates so quickly, it typically leaves minimal residue on the skin once a product has dried.

How It Works

Acetone works through its chemical properties as a volatile solvent. When applied to skin as part of a formulation, it dissolves and carries other ingredients, allowing them to be absorbed or distributed evenly across the surface. Because acetone has a low boiling point (around 56°C), it evaporates rapidly at body temperature and room temperature, which is why products containing it typically dry down quickly.

Its role is largely functional rather than therapeutic—it facilitates the delivery or stability of other active ingredients rather than providing direct skincare benefits itself.

Clinical Evidence & References

There is limited research on acetone as a skincare ingredient specifically. Most scientific attention has focused on related compounds: dihydroxyacetone (DHA), a different chemical used in self-tanning products, which reacts with amino acids in skin to produce colour change. Acetone itself does not function as a tanning agent and should not be confused with DHA.

Acetone's safety profile in cosmetic use is generally established through its widespread use in nail products and industrial applications, but direct clinical studies on its effects within skincare formulations are sparse. Its volatile nature means systemic absorption through the skin is minimal.

How to Use

Products containing acetone should be used as directed on the label. Allow formulations containing this ingredient to dry completely before applying other products, as acetone's rapid evaporation may affect how subsequent layers absorb. Store acetone-containing products in cool conditions away from heat, as acetone is flammable and will evaporate more quickly in warm environments.

Safety & Precautions

Acetone is generally well-tolerated in cosmetic formulations at the concentrations used. It may cause irritation or dryness if applied in high concentrations or to very sensitive skin, and should be avoided near the eye area.

Regulatory information

Standardised cosmetic-ingredient identifiers used by regulators.

Show identifiers
INCI Name
ACETONE
INN Name
acetone
EC Number
200-662-2
Function
Denaturant, Solvent

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