Acetyl Dipeptide-3 Aminohexanoate
INCI: ACETYL DIPEPTIDE-3 AMINOHEXANOATE
Also known as: Acetyl Dipeptide-3 Aminohexanoate
A peptide derivative that supports skin conditioning and hydration
At a glance
Best For Skin Types
All, Dry, Sensitive, Mature
Addresses
Usage Frequency
Daily
What Is Acetyl Dipeptide-3 Aminohexanoate?
Acetyl Dipeptide-3 Aminohexanoate is a synthetic peptide—a short chain of amino acids—designed to function as a skin conditioning agent. It belongs to a broader category of peptide ingredients used in skincare formulations to help maintain skin hydration and support the skin's natural moisture barrier.
This ingredient works at the surface level to help skin retain water and maintain a smooth, supple appearance. It is typically used in concentrations that allow it to integrate into serums, moisturisers, and targeted treatments without causing irritation.
How It Works
Acetyl Dipeptide-3 Aminohexanoate functions as a humectant and conditioning agent. Humectants work by drawing water into the outermost layer of skin, helping it stay hydrated. The peptide structure of this ingredient also allows it to interact gently with skin proteins, supporting the skin's natural moisturising factors.
Because it is a relatively small peptide derivative, it can be used in formulations without creating a thick or occlusive feel, making it suitable for a range of product types and skin concerns.
Clinical Evidence & References
Published clinical evidence specifically on Acetyl Dipeptide-3 Aminohexanoate is limited. Most support for this ingredient comes from its classification as a peptide-based skin conditioner and from the broader evidence base showing that peptides can support skin hydration and barrier function.
The ingredient has a history of use in cosmetic formulations and is generally recognised as safe, but consumers seeking strong clinical proof of efficacy should be aware that dedicated research on this specific compound is sparse. It works best as part of a comprehensive skincare routine rather than as a standalone solution.
How to Use
This ingredient works well in layered routines: apply it after cleansing and toning, either as part of a serum or moisturiser. It pairs well with other humectants (such as glycerin or hyaluronic acid) and occlusive ingredients (such as oils or silicones) to maximise hydration. Use morning and evening for best results, and allow each layer to absorb before applying the next product.
Safety & Precautions
Regulatory information
Standardised cosmetic-ingredient identifiers used by regulators.
Show identifiers
- INCI Name
- ACETYL DIPEPTIDE-3 AMINOHEXANOATE
- EC Number
- -
- Function
- Skin Conditioning
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