Acetyl Glutamic Acid

INCI: ACETYL GLUTAMIC ACID

An amino acid derivative that helps maintain skin's natural moisture and softness

Best For Skin Types

All, Dry, Sensitive, Mature

Addresses

Dryness, Hydration, Sensitivity

Usage Frequency

Daily

What Is Acetyl Glutamic Acid?

Acetyl glutamic acid is a modified form of glutamic acid, a naturally occurring amino acid. In skincare formulations, it functions as a skin conditioning agent, meaning it helps improve the texture and feel of the skin surface.

The ingredient works by supporting the skin's ability to retain moisture and maintain a smooth, supple appearance. It is typically used in small concentrations within moisturisers, serums and other hydrating products.

How It Works

Acetyl glutamic acid functions as a humectant and skin conditioning agent. Humectants are molecules that attract water molecules from the environment and deeper skin layers, helping to bind moisture within the stratum corneum (the outermost layer of skin). This hydrating effect contributes to a smoother, more supple skin surface.

The acetylation (chemical modification) of the glutamic acid molecule may enhance its stability and efficacy within cosmetic formulations compared to unmodified glutamic acid.

Clinical Evidence & References

Acetyl glutamic acid is recognised as a safe skin conditioning ingredient by cosmetic regulatory bodies. However, published clinical research specifically evaluating its efficacy in skincare is limited. Most evidence supporting its use comes from its long history of safe use in cosmetic formulations and its chemical properties as a humectant.

Like other amino acid derivatives, it is generally considered well-tolerated, though individual tolerance may vary depending on skin sensitivity and formulation context.

How to Use

Acetyl glutamic acid is most effective when used as part of a complete hydrating routine. It works well in moisturisers, hydrating serums and essences, where it can be layered with other humectants and emollients to maximise hydration benefits. Apply to clean skin, either alone or as part of your regular skincare regimen.

Safety & Precautions

Acetyl glutamic acid is generally considered safe and well-tolerated in skincare products. No significant adverse effects have been reported at cosmetic use levels. Those with glutamic acid sensitivities should patch test before full application.

Regulatory information

Standardised cosmetic-ingredient identifiers used by regulators.

Show identifiers
INCI Name
ACETYL GLUTAMIC ACID
EC Number
214-708-4
Function
Skin Conditioning

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