Acetyl Hexapeptide-22
INCI: ACETYL HEXAPEPTIDE-22
Also known as: Acetyl Hexapeptide-22
A peptide designed to support skin resilience and reduce visible signs of ageing
At a glance
Best For Skin Types
All, Mature, Sensitive
Addresses
Usage Frequency
Daily
What Is Acetyl Hexapeptide-22?
Acetyl Hexapeptide-22 is a synthetic peptide—a short chain of amino acids designed to mimic natural peptides present in skin. It functions as an antioxidant and skin-protecting agent, helping to defend against environmental stressors whilst supporting the skin's natural repair processes.
This ingredient is used in anti-ageing and skin-conditioning formulations across a range of skincare products, typically at modest concentrations in serums, creams, and treatment preparations.
Benefits for Your Skin
How It Works
Acetyl Hexapeptide-22 works primarily through antioxidant activity, neutralising free radicals that accumulate in skin from environmental exposure and natural metabolic processes. By reducing oxidative stress, it helps prevent and slow the visible signs of ageing.
The peptide also supports skin's natural protective barrier and homeostatic functions, helping maintain skin resilience. However, the precise extent to which topically applied peptides penetrate beyond the skin's surface to exert deeper biological effects remains an active area of research.
Clinical Evidence & References
Research on peptides in skincare shows promise for antioxidant and skin-protective benefits when applied topically. Studies suggest that peptide-based formulations can help reduce oxidative stress and support skin barrier function, though the degree of skin penetration varies depending on peptide size and formulation.
Evidence specific to Acetyl Hexapeptide-22 is limited. Most established data exists for related peptides such as Acetyl Hexapeptide-8, which has been studied for anti-wrinkle effects. While preliminary findings are encouraging, more targeted research on this specific ingredient would help clarify its efficacy at typical cosmetic concentrations.
How to Use
Acetyl Hexapeptide-22 is typically found in serums, creams, and treatment moisturisers designed for anti-ageing. Apply to clean skin morning and evening as part of your regular routine. It works well alongside other antioxidants and can be layered with hydrating or barrier-repair ingredients. Allow products to absorb before applying additional treatments.
Safety & Precautions
Regulatory information
Standardised cosmetic-ingredient identifiers used by regulators.
Show identifiers
- INCI Name
- ACETYL HEXAPEPTIDE-22
- EC Number
- -
- Function
- Antioxidant, Redu CI Ng, Skin Protecting
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