Acetyl Hexapeptide-31

INCI: ACETYL HEXAPEPTIDE-31

Also known as: Acetyl Hexapeptide-31

A peptide designed to support skin conditioning and resilience

At a glance

Peptide

Best For Skin Types

All, Mature, Sensitive

Addresses

Fine lines, Barrier repair, Dryness

Usage Frequency

Daily

What Is Acetyl Hexapeptide-31?

Acetyl Hexapeptide-31 is a synthetic peptide—a short chain of amino acids—created to mimic natural processes that occur in the skin. Peptides of this type are designed to support skin function and structure, working at a molecular level to help maintain the skin's natural barrier and resilience.

This ingredient is classified as a skin conditioning agent, meaning it is intended to improve the texture, appearance, and overall health of the skin surface. It belongs to a broader category of biomimetic peptides that have become increasingly common in modern skincare formulations.

How It Works

Acetyl Hexapeptide-31 functions as a skin conditioning agent by interacting with the skin at the cellular level. The peptide is designed to communicate with skin cells and support their natural maintenance and repair processes, helping to preserve skin resilience and appearance over time.

Because peptides are relatively large molecules, the extent to which this ingredient penetrates beyond the skin surface remains an area of ongoing research. Most evidence suggests that topical peptides primarily work in the upper layers of the skin, though formulation techniques can influence how they interact with skin tissue.

Clinical Evidence & References

Research on peptides in skincare has shown that they can support skin conditioning and appearance when used in topical formulations. However, specific clinical data on Acetyl Hexapeptide-31 in particular is limited, and much of the broader peptide research focuses on related compounds such as acetyl hexapeptide-8.

The evidence available suggests that peptides of this class are generally well-tolerated and can contribute to skin health as part of a comprehensive skincare routine. More targeted research on this specific peptide would help clarify its particular efficacy profile.

How to Use

This ingredient is typically found in creams, serums, and other leave-on skincare products. Apply as directed on the product packaging, usually as part of your morning or evening routine. For best results, use consistently over several weeks, as peptide-based benefits tend to accumulate with regular use. Combine with sunscreen during the day and other targeted treatments suited to your skin concerns for optimal results.

Safety & Precautions

Acetyl Hexapeptide-31 is generally well-tolerated by most skin types. As with any skincare ingredient, patch test if you have particularly sensitive skin or are prone to reactions.

Regulatory information

Standardised cosmetic-ingredient identifiers used by regulators.

Show identifiers
INCI Name
ACETYL HEXAPEPTIDE-31
EC Number
-
Function
Skin Conditioning

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