Acetyl Hexapeptide-7
INCI: ACETYL HEXAPEPTIDE-7
Also known as: Acetyl Hexapeptide-7
A peptide designed to support skin's protective function and resilience
At a glance
Best For Skin Types
All, Sensitive
Addresses
Usage Frequency
Daily
What Is Acetyl Hexapeptide-7?
Acetyl Hexapeptide-7 is a synthetic peptide—a short chain of amino acids—created in the laboratory. Peptides are fragments of proteins, and when applied topically, they are thought to signal the skin to support its natural maintenance and defence processes.
This particular peptide is classified as a skin-protecting ingredient. Rather than directly altering skin appearance, it works at a signalling level, potentially helping the skin maintain its structural integrity and barrier function.
How It Works
Acetyl Hexapeptide-7 is believed to work through a signalling mechanism. When applied to the skin, it may communicate with skin cells to upregulate protective proteins and reinforce the barrier—the outermost layer responsible for holding in moisture and keeping out irritants.
This is distinct from ingredients that directly moisturise or exfoliate; instead, it encourages the skin's own maintenance systems to function optimally, much like a biochemical reminder to maintain defences.
Clinical Evidence & References
Research on Acetyl Hexapeptide-7 is limited compared to better-established ingredients. Some in vitro and small-scale studies suggest it can support skin barrier proteins and reduce inflammatory markers, but large-scale human clinical trials are sparse in the published literature.
The ingredient is generally recognised as safe and well-tolerated in cosmetic formulations, though robust evidence of visible anti-ageing or protective effects in humans remains modest. It is best considered a supportive ingredient rather than a primary active.
How to Use
Acetyl Hexapeptide-7 is typically found in serums, moisturisers, and targeted treatments. Apply to clean skin before heavier creams, or mix into your existing routine. As with any new ingredient, patch test first if you have sensitive skin. Results, if any, develop over consistent use—typically several weeks.
Safety & Precautions
Regulatory information
Standardised cosmetic-ingredient identifiers used by regulators.
Show identifiers
- INCI Name
- ACETYL HEXAPEPTIDE-7
- EC Number
- -
- Function
- Skin Protecting
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.