Acetyl Hexapeptide-71 Amide

INCI: ACETYL HEXAPEPTIDE-71 AMIDE

Also known as: Acetyl Hexapeptide-71 Amide

A peptide that conditions skin and may support firmness when used consistently

At a glance

Peptide

Best For Skin Types

All

Addresses

Fine lines, Firmness, Hydration

Effective Concentrations

Up to 0.005%

Usage Frequency

Daily

What Is Acetyl Hexapeptide-71 Amide?

Acetyl Hexapeptide-71 Amide is a synthetic peptide—a short chain of amino acids—designed to function as a skin conditioning agent in cosmetic formulations. Peptides are commonly used in skincare to support the skin's structural integrity and appearance.

This particular ingredient works at the skin surface and upper layers, where it is thought to help maintain skin condition and support firmness. It is typically used at low concentrations in creams, serums and other topical products.

How It Works

Acetyl Hexapeptide-71 Amide is a peptide that functions as a humectant and skin conditioning agent. It works primarily at the surface and upper layers of the epidermis, where it can help retain moisture and support the skin's natural structure.

The ingredient does not penetrate deeply into the skin in meaningful amounts at the concentrations used in cosmetics, which means its effects are largely limited to surface conditioning and hydration support rather than systemic biological changes.

Clinical Evidence & References

Research on related peptides suggests that peptides can support skin hydration and condition when applied topically. However, evidence specifically for Acetyl Hexapeptide-71 Amide is limited, and most claims around peptide-based anti-aging effects remain modest in scope.

Regulatory bodies have confirmed safety at approved cosmetic concentrations, but the extent of visible benefit will depend on consistent use and individual skin response. Results are typically gradual rather than immediate.

How to Use

For best results, use Acetyl Hexapeptide-71 Amide as part of a consistent daily skincare routine. Apply it to clean, damp skin and follow with a moisturiser to lock in hydration. Most peptide-based products show benefits over weeks to months of regular use rather than days, so patience is important.

Safety & Precautions

Acetyl Hexapeptide-71 Amide is generally well-tolerated in cosmetics at approved concentrations. It is suitable for most skin types, including sensitive skin, though patch testing is always advisable when introducing new products.

Regulatory information

Standardised cosmetic-ingredient identifiers used by regulators.

Show identifiers
INCI Name
ACETYL HEXAPEPTIDE-71 AMIDE
Function
Skin Conditioning

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