Acetyl Octapeptide-29 Amide

INCI: ACETYL OCTAPEPTIDE-29 AMIDE

Also known as: Acetyl Octapeptide-29 Amide

A peptide that conditions skin and supports its structural integrity

At a glance

Peptide

Best For Skin Types

All

Addresses

Dryness, Hydration

Usage Frequency

Daily

What Is Acetyl Octapeptide-29 Amide?

Acetyl Octapeptide-29 Amide is a synthetic peptide—a short chain of amino acids—designed to function as a skin conditioning agent. Peptides are fragments that mimic natural proteins found in skin, and this particular ingredient is formulated to support the skin's appearance and feel.

In skincare products, it works as a humectant and conditioning agent, helping to maintain moisture and improve the overall texture and suppleness of the skin barrier.

How It Works

Peptides like Acetyl Octapeptide-29 Amide work by interacting with the skin's natural proteins and moisture-binding systems. As a conditioning agent, it helps to soften the skin and improve its tactile quality.

The precise mechanism by which this specific octapeptide exerts its effects remains incompletely characterised in published literature, though peptides generally function by supporting the skin's natural moisturisation and protective processes.

Clinical Evidence & References

Published research specifically investigating Acetyl Octapeptide-29 Amide is limited. The evidence base for this ingredient as used in cosmetics is primarily derived from safety assessments and general peptide science rather than dedicated efficacy studies.

Related peptides (such as Acetyl Hexapeptide-8) have been evaluated for safety in cosmetic formulations. Broader peptide research suggests these ingredients can support skin conditioning, though individual formulations and concentrations will influence real-world results.

How to Use

Acetyl Octapeptide-29 Amide is typically found in serums, moisturisers and hydrating treatments. It works well alongside other hydrating or conditioning ingredients and can be used as part of a daily routine. Apply to clean skin, either alone or as part of your layered skincare.

Safety & Precautions

Peptides are generally well-tolerated by most skin types. No significant adverse effects have been documented for this ingredient at typical use concentrations, though patch testing is advisable for those with known sensitivities.

Regulatory information

Standardised cosmetic-ingredient identifiers used by regulators.

Show identifiers
INCI Name
ACETYL OCTAPEPTIDE-29 AMIDE
Function
Skin Conditioning

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