Acetyl Octapeptide-3

Acetyl Octapeptide-3, also known as SNAP-8, is an evolution of Argireline (Acetyl Hexapeptide-8) with two additional amino acids. This extended sequence may provide enhanced muscle-relaxing effects for reducing expression lines.

The peptide works by interfering with the SNARE complex formation needed for neurotransmitter release at the neuromuscular junction. This reduces muscle contraction intensity, softening the appearance of dynamic wrinkles.

Synthetic peptide that is based around octapeptide-3, a peptide complex composed of the amino acids aspartic acid, glutamic acid, glutamine, and methionine. Also known as SNAP-8, this peptide is said to improve the look of signs of ageing formed from repetitive facial expressions, though there’s no independent research supporting this claim. Even if there were independent research, the concentrations used in the company-sponsored testing to support the improvement of signs of ageing was 3-10%, which is far greater than what’s typically present in skin care products. Like all peptides it has water-binding properties and theoretical skin-restoring ability. It may play a role in helping skin look younger, and can help hydrate and smooth skin.