Acetyl Tetrapeptide-71
INCI: ACETYL TETRAPEPTIDE-71
Also known as: Acetyl Tetrapeptide-71
A peptide derivative that supports skin's natural moisture and lipid balance
At a glance
Best For Skin Types
All, Dry, Sensitive, Mature
Addresses
Usage Frequency
Daily
What Is Acetyl Tetrapeptide-71?
Acetyl Tetrapeptide-71 is a synthetic peptide—a short chain of amino acids—designed to mimic natural signalling molecules in the skin. Peptides are thought to communicate with skin cells to support their normal functions, particularly around barrier maintenance and hydration.
This ingredient functions as an emollient and humectant, meaning it helps soften the skin surface and draw moisture into the outer layers. It also acts as a skin conditioning agent, contributing to a smoother texture and improved skin comfort.
How It Works
Peptides like Acetyl Tetrapeptide-71 are believed to work by signalling to skin cells, particularly fibroblasts and epidermal cells, to maintain or enhance their natural functions. The acetyl component may relate to cellular energy and lipid synthesis pathways that are crucial for barrier health.
By supporting the skin's own ability to produce and maintain barrier lipids—the natural fats that hold moisture in—this peptide may help optimise hydration and skin resilience from within.
Clinical Evidence & References
Research into acetyl-related pathways suggests that cellular acetyl metabolism plays a significant role in skin barrier function and lipid homeostasis. Studies indicate that the skin's lipid production is tightly regulated and essential for barrier integrity and moisture retention.
However, specific clinical data on Acetyl Tetrapeptide-71 itself in human studies remains limited. Most evidence is derived from biochemical and cellular research rather than large-scale human trials, so claims about its efficacy should be viewed with appropriate caution.
Published Research
How to Use
This ingredient is typically found in serums, moisturisers and barrier-repair products at concentrations that support its humectant and conditioning functions. Apply to clean skin, either alone or layered with other hydrating products. It pairs well with other peptides and hydrating ingredients like glycerin or hyaluronic acid for enhanced moisture support.
Safety & Precautions
Regulatory information
Standardised cosmetic-ingredient identifiers used by regulators.
Show identifiers
- INCI Name
- ACETYL TETRAPEPTIDE-71
- Function
- Emollient, Humectant, Skin Conditioning, Skin Protecting
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