Acetyl Tripeptide-59 Amide

INCI: ACETYL TRIPEPTIDE-59 AMIDE

Also known as: Acetyl Tripeptide-59 Amide

A peptide-derived skin conditioning agent used in cosmetic formulations

At a glance

Peptide

Best For Skin Types

All

Addresses

Dryness, Hydration

Usage Frequency

Daily

What Is Acetyl Tripeptide-59 Amide?

Acetyl Tripeptide-59 Amide is a synthetic peptide—a short chain of amino acids—designed for use in skincare products. Peptides are fragments of proteins, and this particular variant is engineered to function as a skin conditioning agent.

In formulations, it works to improve the texture and feel of products whilst supporting the skin's surface condition. It is typically used in very small concentrations within cosmetic preparations.

How It Works

Acetyl Tripeptide-59 Amide functions as a humectant and conditioning agent. Its peptide structure allows it to interact with the skin's outer layer, helping to bind and retain moisture at the surface. This can contribute to a smoother appearance and improved skin feel.

The ingredient does not penetrate deeply into the skin; rather, it works primarily on the stratum corneum—the outermost layer—to optimise hydration and texture.

Clinical Evidence & References

Published research specifically on Acetyl Tripeptide-59 Amide is limited in the public domain. However, safety assessments of closely related peptides (such as Acetyl Hexapeptide-8 Amide) have been conducted by cosmetic ingredient safety panels, which have established that peptides of this type are safe at typical use concentrations.

The evidence base suggests that these peptide-derived conditioning agents are well-tolerated in topical formulations, though research on specific efficacy claims for this particular tripeptide variant remains sparse.

How to Use

Apply as directed within the full product formulation. Because Acetyl Tripeptide-59 Amide is used at minimal concentrations within formulations rather than as a standalone treatment, there is no specific usage protocol beyond following the instructions of the skincare product containing it.

Safety & Precautions

Acetyl Tripeptide-59 Amide is generally well-tolerated as a skin conditioning agent in cosmetic formulations. No specific contraindications have been identified at typical use levels.

Regulatory information

Standardised cosmetic-ingredient identifiers used by regulators.

Show identifiers
INCI Name
ACETYL TRIPEPTIDE-59 AMIDE
Function
Skin Conditioning

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