Acetyl Zingerone
INCI: Zingerone, Curcumin
Also known as: Zingerone, Curcumin
Potent, ginger-derived antioxidant Helps offset numerous visible signs of ageing from environmental damage
Best For Skin Types
All skin types
Usage Frequency
As directed on product packaging
EWG Safety Score
What Is Acetyl Zingerone?
Acetyl zingerone is a ginger-derived antioxidant that serves as an “omni-antioxidant” because it’s able to scavenge and neutralize a broad range of free radicals known to impair skin’s health and appearance. Research on human skin and skin cells has shown acetyl zingerone helps offset the negative impacts of environmental damage, helps visibly repair, and nurtures skin’s ability to maintain the integrity of the extracellular matrix for a healthy appearance.
In vivo clinical data on people has shown measurable improvements in wrinkles, redness, and hyperpigmentation within four weeks of use.
It’s particularly good at soothing UV-exposed skin, interrupting the cascade of damage it causes on and within skin’s surface layers. This antioxidant has excellent photostability (remains stable for longer when exposed to UV light) and along with fading UV-induced discoloration, it also targets mottled pigmentation due to exposures across the visible light spectrum, meaning it helps protect skin from visible (blue or HEV) light exposure.
Acetyl zingerone also delivers anti-pollution benefits, including from “urban dust” (small particulate matter that often contains collagen-degrading heavy metals). It also helps interrupt the damage certain enzymes in skin can cause to our collagen, thus preserving a youthful look for longer and helping to reduce lines and wrinkles.
In vitro testing has shown acetyl zingerone is capable of influencing factors within skin that promote longevity, keeping skin humming along as the years go by. It benefits skin’s microbiome, too, since this ingredient was shown to support a balance of surface bacteria known to keep skin healthy.
Usage levels in cosmetics range from 0.5–1% if the primary goal is antioxidant, anti-ageing, longevity and microbiome-supporting benefits benefit. Acetyl zingerone is also a chelating agent when used at levels between 0.1%–0.2%.
Additional studies have shown acetyl zingerone has good synergy with a vitamin C derivative (ester) known as tetrahexyldecyl ascorbate. It aids stabilization and the duo produces statistically significant results (compared to this form of vitamin C used alone) on wrinkles, skin tone and discolorations.
Note that despite being ginger-derived, this ingredient is considered synthetic since its molecular structure incorporates elements from a compound in ginger known as zingerone and the plant-derived soothing agent curcumin. It’s best characterized a lab-designed antioxidant that offers more potency and stability than what’s found in the ginger plant.
Benefits for Your Skin
How It Works
Clinical Evidence & References
Published Research
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Acetyl zingerone: A potent antioxidant for skin Free Radic Biol Med, 2017
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