Alanine/Histidine/Lysine Polypeptide Copper Hcl

INCI: ALANINE/HISTIDINE/LYSINE POLYPEPTIDE COPPER HCL

Also known as: Alanine/histidine/lysine Polypeptide Copper Hcl

A copper-binding peptide complex designed to support skin conditioning and resilience

At a glance

Peptide

Best For Skin Types

All

Addresses

Dryness, Texture, Skin resilience

Usage Frequency

Daily

What Is Alanine/Histidine/Lysine Polypeptide Copper Hcl?

Alanine/Histidine/Lysine Polypeptide Copper HCl is a peptide complex that combines three amino acids—alanine, histidine, and lysine—with copper in a chelated form. Peptides are short chains of amino acids that can penetrate the skin's outer layers and communicate with skin cells to influence their behaviour.

In skincare formulations, this ingredient functions as a skin conditioner, meaning it works to improve the texture, feel, and overall condition of the skin surface. The copper component may contribute additional properties, as copper plays a role in collagen synthesis and antioxidant defence within the skin.

How It Works

The peptide component penetrates the upper layers of the epidermis and can interact with skin cells, potentially signalling them to maintain or improve their structural integrity. Histidine and lysine in particular are amino acids involved in collagen and elastin synthesis, though the extent to which this occurs with topical application remains limited in scope.

The chelated copper is bound to the peptide structure in a form designed to remain stable in formulation whilst allowing the copper to participate in enzymatic reactions that support skin resilience and protection against oxidative stress.

Clinical Evidence & References

Published clinical evidence specifically for this peptide complex is limited. The ingredient appears in a small proportion of skincare products, and peer-reviewed studies on its efficacy are sparse.

Evidence supporting peptides and copper in skincare is more general: peptides are recognised as having the potential to improve skin hydration and elasticity, whilst copper is known to support collagen cross-linking and antioxidant defence. However, claims about this specific formulation would require dedicated clinical studies to substantiate. If you are considering products containing this ingredient, it is reasonable to evaluate them on their broader formula and any clinical data the manufacturer provides.

How to Use

This ingredient is typically found in serums, moisturisers, and targeted treatments. Use as directed on the product label. As with any peptide-containing product, consistency over time is more likely to yield results than sporadic use. It can be layered with other skincare actives, though patch testing is advisable if you have sensitive skin or are using multiple active ingredients.

Safety & Precautions

This ingredient is generally well-tolerated in cosmetic formulations. Copper, when chelated and used in appropriate concentrations, is considered safe for topical application. Patch test before full application if you have known sensitivity to copper or peptides.

How widely it's used

0.1%
of skincare products contain this ingredient .
Most common in: Treatments Cleansers

Regulatory information

Standardised cosmetic-ingredient identifiers used by regulators.

Show identifiers
INCI Name
ALANINE/HISTIDINE/LYSINE POLYPEPTIDE COPPER HCL
Function
Skin Conditioning

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