Alanyl Glutamine

Alanyl glutamine is a dipeptide formed by linking two amino acids: alanine and glutamine. This combination is more stable in cosmetic formulations than free glutamine alone, making it a practical choice for skincare products. The ingredient functions as a humectant, drawing moisture into the skin, and as a skin conditioning agent.

Amino acids play a fundamental role in skin structure and function. Glutamine in particular is involved in protein synthesis and cellular metabolism, whilst alanine supports the skin's natural amino acid profile. When combined as a dipeptide, alanyl glutamine may help maintain skin hydration and support the skin's natural protective mechanisms.

As a humectant, alanyl glutamine works by drawing water from the deeper layers of skin and the environment into the outermost layers, helping to maintain hydration. This is a straightforward physical mechanism that supports skin plumpness and appearance.

At a cellular level, glutamine is involved in amino acid metabolism and protein synthesis. When applied topically, the ingredient provides amino acids that support the skin's natural repair and maintenance processes. The dipeptide form offers better stability in cosmetic products compared to free glutamine, which degrades more readily in solution.

Alanyl glutamine is typically found in hydrating serums, moisturisers and essences. Because it works as a humectant, it performs optimally when applied to damp skin or layered with other hydrating products. There is no established upper limit for use, and it can be incorporated into daily skincare routines. It pairs well with other humectants and hydrating ingredients, though there are no specific contraindications with other skincare actives.