Ceramides
INCI: ceramide AP, ceramide EOP, ceramide NG, ceramide NP, ceramide NS, phytosphingosine, sphingosine
Also known as: ceramide AP, ceramide EOP, ceramide NG, ceramide NP, ceramide NS, phytosphingosine, sphingosine, Ceramide NP, Ceramide AP, Ceramide EOP
Major components of skin’s outer layers Help improve barrier strength, hydration, and suppleness
Best For Skin Types
All skin types
Effective Concentrations
0.5-3%
Usage Frequency
As directed on product packaging
EWG Safety Score
What Is Ceramides?
Ceramides are naturally occurring, long chains of lipids (fats) that are major components of skin’s outer layers. In fact, the composition of healthy skin is made up of approximately 50% ceramides. Think of them as the mortar between your skin cells, forming a protective layer that limits moisture loss and protects against visible damage from pollution and other environmental stressors. When ceramide levels decrease (due to ageing and other factors), skin is more vulnerable to external stimuli and various disorders.
As skin care ingredients, ceramides can be derived from plants or bio-identical forms can be created synthetically—both types work effectively (assuming they’re in a well-formulated product). Ceramides are known for their water-retention capacity (think hydration) and adding them to a skin care product helps provide replenishing and restorative benefits. Of note, they help strengthen skin’s barrier and can improve elasticity.
Ceramides work best when combined with other replenishing ingredients like fatty acids and cholesterol. These lipid mixtures work in multiple ways to improve skin’s texture, suppleness, and help calm signs of sensitivity. Different classes of ceramides have been identified in skin. Examples of those used in skin care include ceramide AP, ceramide EOP, ceramide NG, ceramide NP, ceramide NS, phytosphingosine, and sphingosine. To one degree or another, all of them play signaling roles that help to keep skin healthy. The Cosmetic Ingredient Review Expert Panel’s 2020 assessment concluded that ceramide ingredients are safe in cosmetics in the present practices of use. Concentrations vary by the individual ceramide, but generally in skin care they’re used in amounts less than 1%, often much lower since it doesn’t take much to obtain ceramide’s numerous benefits.
. Ceramides are waxy lipid molecules naturally present in the stratum corneum, the outermost layer of skin, where they play a crucial role in barrier function. They work synergistically to increase skin hydration and promote optimal barrier integrity. Beyond hydration, ceramides help combat dryness and irritation. Modern formulations use synthetic ceramides that are bioidentical to the skin's natural ceramides. As essential lipids, they maintain the structure and function of the moisture barrier, keeping skin plump and soft whilst reducing the appearance of fine lines and wrinkles. Ceramides are safe for all skin types and help soothe skin whilst promoting healthy barrier function.Benefits for Your Skin
Clinical Evidence & References
- International Journal of Toxicology, 2020, pages 5S-25S
- Biochimica et Biophysica Acta, October 2014, pages 2473-2483
- Journal of the American Academy of Dermatology, July 2014, pages 177-184
- Journal of Lipid Research, July 2008, pages 1,466-1,476
- Journal of Lipid Research, September 2007, pages 1936-1943
- American Journal of Clinical Dermatology, Volume 4, 2003, pages 107-129
- Journal of Investigative Dermatology, November 2001, pages 1,126-1,136
- Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271
Published Research
-
Ceramides and Skin Function American Journal of Clinical Dermatology, 2017
-
The role of ceramides in skin barrier function Journal of Lipid Research, 2008
How to Use
Safety & Precautions
Learn More About Skincare Ingredients
Explore our comprehensive ingredient glossary to understand what's in your products.
Browse All IngredientsShop Our Products
Find professional skincare solutions at Skintique.