Decapeptide-52
INCI: peptide 14
Also known as: peptide 14, OS-01
Also called peptide 14 or OS-01
At a glance
EWG Safety Score
What Is Decapeptide-52?
Decapeptide-52, also called peptide 14 and referred to by cosmetic brand OneSkin as "OS-01", is an exclusive peptide used extensively in the company's products. OneSkin claims this peptide interrupts the process of cellular senescence. This process occurs when cells that have stopped proliferating (sometimes referred to as "zombie cells") send out pro-aging factors to surrounding cells, creating a waterfall effect that leads to visible signs of aging. In essence, the ongoing presence of senescent cells gets the good cells to do bad things that impact skin's health and appearance.
Limited research at this time indicates decapeptide-52 might indeed be able to interrupt the process of cellular senescence, though it must be noted that most studies have been conducted by either OneSkin (which developed this peptide) or people associated with the brand. While we're cautiously optimistic about the potential of this ingredient, more independent studies must be conducted before determining if it's a must-add to your skin care routine.
Clinical Evidence & References
Published Research
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OneSkin.com, Website, Accessed October 2024 OneSkin.com, 2024
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NPJ Aging, May 2023, ePublication NPJ Aging, 2023
Regulatory information
Standardised cosmetic-ingredient identifiers used by regulators.
Show identifiers
- INCI Name
- DECAPEPTIDE-52
- Function
- Skin Conditioning
Related Ingredients
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Acetyl Glycyl Beta-Alanine
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Acetyl Hexapeptide-1
A synthetic peptide Composed of the amino acids
Acetyl Hexapeptide-37
Synthetic peptide Composed of amino acids (alanine, proline, serine, and glycine)
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