Glycyrrhetinic Acid
Also known as: Glycyrrhiza Glabra
Main ingredient found in licorice | Potent antioxidant properties
Addresses
EWG Safety Score
What Is Glycyrrhetinic Acid?
Glycyrrhetinic acid is a bioactive compound that’s the main active ingredient found in the licorice plant (Glycyrrhiza glabra). While it’s most famously known for imparting licorice’s signature flavor, it’s also an important ingredient for maintaining healthy skin.
Scientific research demonstrates glycyrrhetinic acid has potent antioxidant properties to fight against the ravages of free-radical damage on skin. Recent studies show this acid is particularly effective in staving off the effects of UVB (ultraviolet B)-induced skin damage.
As if that weren’t impressive enough, research demonstrates glycyrrhetinic acid also exerts impressive anti-inflammatory effects on skin when applied topically. An indirect but often visible result of this trait is the minimization of dark patches and uneven tone.
The independent Cosmetic Ingredient Review panel has ruled glycyrrhetinic acid safe as used in cosmetics, where it is used in concentrations up to 2%. In fact, amounts even as high as 6% showed no indication of skin sensitization or irritation. Common use levels tend to fall between 0.5–1%, especially if this ingredient is used to support other ingredients known to fade hyperpigmentation and/or soothe skin.
Benefits for Your Skin
Clinical Evidence & References
Published Research
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ScienceDirect.com, Website, Accessed August 2024 [URL]
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Biological Chemistry, April 2024, pages 407-415 [URL]
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Bioorganic & Medicinal Chemistry Letters, November 2022, ePublication [URL]
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Mediators of Inflammation, January 2021, pages 1-17 [URL]
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International Journal of Cosmetic Science, August 2019, pages 325-331 [URL]
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International Journal of Toxicology, March 2007, pages 79-112 [URL]
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