Oligopeptide-76
Also known as: SpecPed® O76P
Made up of 13 amino acids | Helps improve skin barrier
Addresses
EWG Safety Score
What Is Oligopeptide-76?
Oligopeptide-76 is a synthetic peptide comprised of 13 amino acids - alanine, aspartic acid, glutamic acid, glycine, isoleucine, leucine, lysine, phenylalanine, and serine. While there isn’t an extensive amount of research on oligopeptide-76’s performance in skin care products, what does exist is very interesting. In addition to the usual skin barrier improvement that most peptides provide, there is evidence suggesting that oligopeptide-76 has antimicrobial properties, including against Cutibacterium acnes, the organism whose pathogenic strains are chiefly responsible for acne breakouts. Oligopeptide-76 is also known by its trade name, SpecPed® O76P. The recommended use level of oligopeptide-76 in cosmetics is 0.001-0.1%, a testament to its potency.
Benefits for Your Skin
Clinical Evidence & References
Published Research
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Covalo, Website, Accessed November 2025 [https://covalo.com/]
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Biologics, May 2025, pages 1-17 [https://www.mdpi.com/2673-8449/5/2/15]
Related Ingredients
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Acetyl Hexapeptide-1
A synthetic peptide Composed of the amino acids
Acetyl Hexapeptide-37
Synthetic peptide Composed of amino acids (alanine, proline, serine, and glycine)
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