Syn-Ake
INCI: Dipeptide Diaminobutyroyl Benzylamide Diacetate
Also known as: Dipeptide Diaminobutyroyl Benzylamide Diacetate, Snake Peptide, Syn-Ake
The wrinkle relaxer
Best For Skin Types
All skin types
Addresses
Effective Concentrations
1-4%
Usage Frequency
As directed on product packaging
EWG Safety Score
What Is Syn-Ake?
Syn-Ake (dipeptide diaminobutyroyl benzylamide diacetate) is a synthetic tripeptide that mimics the effect of waglerin-1, a peptide found in temple viper snake venom. It works by blocking the transmission of nerve signals to facial muscles.
By interfering with muscle contraction at the neuromuscular junction, Syn-Ake helps reduce the appearance of expression lines and wrinkles, particularly those caused by repeated facial movements like smiling or frowning.
Clinical studies have shown that Syn-Ake can reduce wrinkle depth by up to 52% over 28 days of use. Unlike Botox injections, it does not completely paralyze muscles but rather softens the intensity of contractions, resulting in a more natural appearance.
Syn-Ake works best on dynamic wrinkles and is most effective when applied consistently to areas prone to expression lines. It can be combined with other peptides like Argireline for enhanced results.
. This powerful anti-ageing peptide helps prevent and reduce fine lines and expression wrinkles around the eyes, mouth, and forehead. It works by reducing muscle contraction frequency through decreasing acetylcholine binding at neurotransmitter receptor sites. By reducing these muscle contractions, it helps prevent and diminish the appearance of expression lines.Benefits for Your Skin
Clinical Evidence & References
This ingredient is backed by moderate clinical research supporting its effectiveness.
Published Research
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Kojic acid applications in cosmetic and pharmaceutical preparations Biomedicine & Pharmacotherapy, 2019
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Evaluation of the efficacy of kojic acid skin lightening products Journal of Cosmetic Dermatology, 2011
How to Use
Safety & Precautions
Related Ingredients
Acetyl Dipeptide-1 Cetyl Ester
Lab-made anti-ageing peptide that promotes firmer skin Bio-identical to a skin-natural peptide that aids elasticity
Acetyl Glycyl Beta-Alanine
Peptide for reducing skin redness and sensitivity
Acetyl Hexapeptide-1
A synthetic peptide Composed of the amino acids
Acetyl Hexapeptide-37
Synthetic peptide Composed of amino acids (alanine, proline, serine, and glycine)
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