Teprenone

Teprenone, also known as geranylgeranylacetone, is a type of compound known as an acylic polyisoprenoid, a linear rather than a cyclic, ring-shaped molecule. Since 1984, it has been used as a treatment for gastric ulcers in Japan and other Asian countries under the brand name Selbex.

In addition to its gastro-protective properties, science has found teprenone useful in a variety of additional applications. Of note is its antioxidant and anti-inflammatory properties, indicating usefulness when it comes to anti-ageing. A recent study even found that teprenone has the ability to inhibit melanin synthesis, meaning it could become an effective treatment for skin discolourations caused by the overproduction of melanin.

From a skin longevity standpoint, teprenone seems to play a role in reducing multiple intrinsic factors that can cause skin to look prematurely aged, especially from direct exposure to UV light. As such, it may have benefits for restoring a firmer, less lined look and feel to damaged skin.

The recommended use level of teprenone in cosmetics is 3% when combined with the emollient caprylic/capric triglyceride.

Written by: Mercedes Santaella-Lam

Updated on: November 20, 2024